Systems don't run forever
A radon system isn't something you install once and forget. The fan is a mechanical part that runs 24/7, and most last somewhere in the range of five to ten years before the motor wears out. When a fan quietly dies, the system stops protecting the home, but nothing obvious changes inside, so it can go unnoticed until someone checks.
If you bought a home with a system already in place, or yours has been running for years, it's worth confirming it still works rather than assuming it does.
How to tell if yours is working
Most systems have a manometer, a small U-shaped tube of colored liquid mounted on the vent pipe. If the two sides are level, the fan has likely stopped and the system isn't running; if they're offset, it's pulling suction. That gauge tells you the fan is on, but it doesn't tell you the radon level is actually low, which is why the EPA recommends re-testing every two years even with a working system. If a re-test comes back high despite the fan running, the system may need another suction point or other adjustments to keep up.